 | | Cardiovascular Exchange Summit 2011 |
|  | | Definitions |
|
 | | Global Burden of Obesity |
|  | | Trends in adult obesity from around the world |
|
 | | Type 2 Diabetes (T2DM) |
|  | | Obesity and Type 2 Diabetes |
|
 | | Diabetes and Weight Loss |
|  | | The Need to Feed |
|
 | | NICE clinical guideline 43 |
|  | | Treatment options |
|
 | | BARIATRIC SURGERY NICE GUIDELINES (CG43) |
|  | | Dieting vs. Bariatric Surgery |
|
 | | Procedures |
|  | | Types of Bariatric Surgery |
|
 | | Percent of excess weight lost post-surgery |
|  | | Health Benefits of Bariatric Surgery |
|
 | | Resolution of co-morbidities |
|  | | Risks of Bariatric Surgery |
|
 | | Nutritional Deficiencies |
|  | | Effect of operation on DM |
|
 | | T2DM & Bariatric Surgery |
|  | | Metabolic Surgery |
|
 | | Roux-en Y Gastric Bypass (RYGBP) ‘Gold standard’ |
|
|
 | | Gut hormones control body weight& blood sugar |
|  | | Ghrelin: a unique orexigenic hormone |
|
 | | Ghrelin stimulates hunger and food intake in normal-weight volunteers |
|  | | Obese subjects have reduced ghrelin levels |
|
 | | Peptide YY (PYY) |
|  | | Obese humans and mice have low circulating levels of PYY |
|
 | | Glucagon-like peptide 1 (GLP-1) |
|  | | Liraglutide |
|
 | | Liraglutide |
|  | | Increased food availability |
|
 | | PYY3-36 modulates homeostatic and reward regions |
|  | | Ghrelin modulates neuronal activity in homeostatic and reward regions |
|
 | | Role of ghrelin in obesity |
|  | | PYY and Dieting |
|
|
|
|  | | Ghrelin and Bariatric Surgery |
|
 | | Gastric bypass surgery reduces hunger and increases satiety |
|  | | Study Design |
|
 | | Anthropometric Data |
|  | | Appetite Ratings |
|
 | | Changes in PYY post-RYGB |
|  | | Changes in GLP-1 post-RYGB |
|
 | | Changes in acyl-ghrelin post-RYGB |
|  | | Are the changes in PYY3-36 and active GLP-1 due to weight loss? |
|
 | | Metabolic Surgery in T2DM with BMI ≤ 35 kg/m2 |
|  | | International Diabetes Federation |
|
 | | Take home messages |
|  | | How Does Obesity Surgery Cause Weight Loss and Cure Type 2 Diabetes? |
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