Cardiovasculaire Geneeskunde.nl

Genes for CV risk prediction & treatment: Fact or fiction?

Slides (presentatie) - Nov. 9, 2011

Genes for CV risk prediction & treatment: Fact or fiction?


Prof. Steve Humphries – Professor of Cardiovascular Medicine
University College London
 


Bekijk of download de presentatie

klik voor bekijken op onderstaande afbeeldingen




Cardiovascular Exchange Summit 2011

NORTHWICK PARK HEART STUDY II

RISK SCORE METHODS - PROCAM/Framingham

CRFs Predict Poorly in UK Middle-Aged Men

CRP : Origin, Clearance and Function

Adding CRP to algorithm Risk Score in NPHSII

Will genotype predict risk over-and-above trait

Genome Wide Scans – case control approach

Major New “Gene” for MI/CHD Identified on Chromosome 9

Is Chr9 SNP CHD risk effect robust?

ROC to test predictive power

Chr9 SNP and Risk Prediction in NPHSII men

SEVEN GWAS SNPs FOR CHD RISK IDENTIFIED

Current CHD GWAS loci

Combining Modest-Risk Genotypes – Gene Score

Distribution of Risk alleles in NPHSII men

Where is the rest of the Genetic contribution ?

ELSI - Risk Perception and Behaviour Change

CARE PATHWAY FOR CARDIOVASCULAR RISK CLINIC

Deze inhoud is bedoeld voor medische professionals. Om dit te bekijken is registratie noodzakelijk. Registreer gratis voor onbeperkte toegang tot ons educatief materiaal.

Deel deze pagina met collega's en vrienden: